Recent contributions of molecular biology to the clinical virology of myxoviruses.
Identifieur interne : 002772 ( Main/Exploration ); précédent : 002771; suivant : 002773Recent contributions of molecular biology to the clinical virology of myxoviruses.
Auteurs : E. D. KilbourneSource :
- The Yale Journal of Biology and Medicine [ 0044-0086 ] ; 1980.
Abstract
Recent advances in the clinical virology of influenza are based on non-pragmatically oriented research on the genetics and biochemistry of the influenza virus. Antigenically hybrid recombinant viruses can be tailored to provide monospecific reagents for serological studies. Basic research on viral structure and the mechanism of viral replication has directly influenced the establishment of a cell culture system suitable for the isolation of most influenza viruses. Identification of viral genotype by RNA gel electrophoresis and mapping of oligonucleotides of viral RNA has already facilitated epidemiologic investigations. The clinical virologist of the future must have an understanding of the potential limitations of these techniques for specific strain identification.
Url:
PubMed: 6990635
PubMed Central: 2595840
Affiliations:
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Le document en format XML
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